منابع مشابه
Pernicious anaemia.
DEFICIENCY of vitamin B12 (cyanocobalamin) in man results in a macrocytic animia, leucopa2nia, the appearance of megaloblasts and giant band cells in the marrow, reduced formation of platelets, and also-changes in the peripheral and central nervous systems. In temperate climates the most common cause of vitamin B12 deficiency is pernicious anaemia. This is by no means a rare disease, having an ...
متن کاملJuvenile pernicious anaemia.
The extreme rarity of pernicious anaemia in childhood has been stressed by Lambert, Prankerd, and Smellie (1961) who, by insisting on positive evidence of intrinsic factor deficiency for the diagnosis, could accept unequivocally only 7 cases in the literature but added 2 of their own, who were sibs. They may have overlooked the case described by Wilkins (1957) which was later confirmed by McInt...
متن کاملDisguised pernicious anaemia.
exacerbation of the adrenal insufficiency with return of anorexia, lassitude, loss of weight, and low blood pressure. Although patients with Addison's disease, treated with cortisone, are not usually hypersensitive to insulin, in this present case, as the patient's condition improved satisfactorily, and her insulin sensitivity was uncertain, the latter drug was not used immediately. It is inter...
متن کاملPernicious Anaemia and B12 Deficiency
Gastric causes: gastrectomy, gastric resection, atrophic gastritis, H. pylori infection or congenital IF deficiency or abnormality. Inadequate dietary intake of vitamin B12 eg, a vegan diet. Intestinal causes eg, malabsorption, ileal resection, Crohn's disease affecting the ileum, chronic tropical sprue, HIV and any radiotherapy causing irradiation of the ileum. Drugs eg, colchicine, neomycin, ...
متن کاملRheumatoid arthritis and pernicious anaemia.
There are reports of an association between megaloblastic anaemia and rheumatoid arthritis. Partridge and Duthie (1963) found megaloblastic anaemia in 1 38 per cent. (35 cases) of 2,544 rheumatoid arthritis patients, as opposed to 0-27 per cent. (15 cases) of 5,515 controls. Of the 35 rheumatoid patients with megaloblastic anaemia, 27 were thought to have Addisonian pernicious anaemia, an incid...
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ژورنال
عنوان ژورنال: BMJ
سال: 1927
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.3458.719